Should You Worry About Artificial Flavors Or Colors? Patients with prior musculoskeletal or neuromuscular complains, and family history of muscular disorders were excluded. Therefore, atorvastatin given on alternate days may be … 9/11 Truther Mark Ruffalo Testifies to Congress on Science, Nothing Grimes Said About Eyeballs or Depression Makes Any Sense, Jeff Bezos' Plan to Colonize Space is Based on Sheer Nonsense, Robert F. Kennedy, Jr. is Helping Spread Flu and Cervical Cancer, Anti-Monsanto Lawyer and USRTK, Carey Gillam Collaborator Possibly Headed to Prison for Extortion, Journalist Peter Fairley Cites Anti-Vaxx Website, Spreads Misinformation on Flu, COVID-19, DeSmogBlog: Climate Website Is Headed by Anti-Vaxxer Brendan DeMelle, DeSmogBlog: Climate Activist Site Smears Freeman Dyson and Other Scientists. Alternate-Day Statin Dosing May be as Effective, and Cheaper, The Next Plague and How Science Will Stop It. A sample size of 400 patients between the age of 40–70 years, taking simvastatin 40 mg for at least 6 months or more were selected. There is evidence favoring primary prevention with statins for high-risk patients. Don't Panic, Everything Goes to Pot: Myths Are Driving FDA, CDC Vaping Policy, What the Hulk? The size of the decrease has been shown to be similar to that seen in patients receiving daily statin therapy. Of the patients experiencing myalgia, 13 (6.5%) from the EDD group and 6 (3%) from the ADD group had low levels of vitamin D. ADD regime was better tolerated by the patients than EDD regime. Advertising Policy. COPYRIGHT © 1978-2020 BY THE AMERICAN COUNCIL ON SCIENCE AND HEALTH. Here is some good news for those of you among the millions taking statins you may not need to take them daily. Data was analyzed through SPSS 16.0 and compared using chi square test. Most of studies reviewed demonstrated that when compared with baseline, every-other-day dosing of statins significantly lowered low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglyceride (TG) levels. [7,8] Thus, it is conceivable that alternate-day treatment might be effective in maintaining the lipid-lowering efficacy of atorvastatin. By continuing you agree to the use of cookies. Further supporting this concept is the fact that total cholesterol … No treatment is without some risk. Statins are widely used drugs, known to cause myalgia, leading to high discontinuation rates. This cross sectional study was conducted in a tertiary care hospital of Pakistan. Hence, to achieve better patient compliance and reduce the incidence of myalgia physicians should consider ADD. Background: Although most patients with hypercholesterolemia require life-long therapy with statins, these drugs are underused due to high costs. The parallel is seen most consistently in patients in the alternate-day … The most common cited triggering factor for pain was physical exercise. Contributions are fully tax-deductible. Helping Smokers Quit: The Science Behind Tobacco Harm Reduction, Foods Are Not Cigarettes: Why Tobacco Lawsuits Are Not a Model for Obesity Lawsuits, The Prevention and Treatment of Osteoporosis: A Review. New cholesterol guidelines suggest a statin may be in your future, Dispatch: For Those With High Cholesterol: Nuts to You, Perceptions of statin side-effects greatly outnumber actual threat, Concussion Prevention: Sorting Through the Science to See What's Sound, No Evidence that Blue-Light Blocking Glasses Help with Sleep, Dutch Newspaper 'De Telegraaf' Accuses Scientists of Being Corporate Publicists. ACSH s Dr. Josh Bloom adds, This makes sense, since not only are the half-lives of statins fairly long, but as a secondary effect to inhibiting cholesterol biosynthesis, the liver expressed more LDL receptors, which help clear LDL (bad cholesterol).

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